A NEW STANDARD OF CARE FOR THE TREATMENT OF CHEMOTHERAPY-INDUCED DIARRHEA (CID) IN DOGS
Only FDA conditionally approved product to treat chemotherapy-induced diarrhea (CID) in dogs
WHAT IS Canalevia-CA1?
Canalevia-CA1 normalizes water flow to reinstate normal function in the GI tract and is an antidiarrheal, enteric-coated tablet for oral administration. It acts locally and it is not absorbed into the blood stream, providing a well tolerated and non-toxic drug product.
First in Class Anti-Diarrheal
Normalizes Water Flow in the Gut
Canalevia-CA1 is a plant-based treatment of chemotherapy-induced diarrhea in dogs.
Diarrhea is one of the many side effects during chemotherapy treatment for cancer patients. Diarrhea can delay treatment and reduce completion of the patient’s full course of therapy.
Crofelemer, the active ingredient in Canalevia-CA1, acts within the lumen of the GI tract.
Crofelemer is an inhibitor of two chloride ion (Cl ) channels at the luminal membrane of enterocytes. These channels are responsible for the regulation of Cl influx into the lumen. Crofelemer inhibits the hypersecretion of Cl in chemotherapy-induced diarrhea and normalizes the water influx into the GI tract.
WHAT IS HAPPENING TO MY DOG?
PROVIDING COMFORT AND EASING THE BURDEN OF CHEMOTHERAPY-INDUCED DIARRHEA (CID)
IN DOGS FOR THE...
SUPPORTING CONTINUED TREATMENT
Treating CID in dogs undergoing chemotherapy prevents interruption in their treatment plan. You can keep your patient on track completing their full course of therapy.
COST AND TIME SAVINGS
Inhibiting CID in your pet reduces the incidence of accidents around the home that cause costly damages, missed days at work and future vet visits. You can spend more time caring for your pet and less time cleaning spontaneous messes.
QUALITY OF LIFE
CID can induce distress and suffering in sensitive animals like dogs. Alleviating CID can improve the quality of life for dogs undergoing an already traumatic experience, and reduces the chance of extra visits to the veterinarian.
KEY BENEFITS OF Canalevia-CA1
Ease the Burden
A planned CID treatment reduces costly accidents around the home, and improves the quality of life for dogs undergoing chemotherapy and their owners.
Reduces the instances of watery stools.
A well-tolerated treatment.
Modulates the hypersecretion of CI in CID and normalizes water influx into the intestinal lumen.
Only FDA conditionally approved product for chemotherapy-induced diarrhea (CID) in dogs.
Approximately 1 in 4 dogs will, at some stage in their life, develop neoplasia. 1
Canalevia-CA1 is well tolerated with only a three-day course of treatment.
Alleviating CID improves the quality of life for dogs undergoing an already traumatic experience.
1 AVMA. “Cancer in Pets.” AVMA, www.avma.org/resources/pet-owners/petcare/cancer-pets. Accessed 21 Dec. 2021.